Drug interactions
Ganaxolone + Voriconazole
Severity: Minor
Ganaxolone and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ganaxolone is metabolized by CYP3A4, but labeling indicates CYP3A4 inhibitors do not meaningfully change its exposure. No clinically significant interaction is expected.
What this interaction means in plain words
Ganaxolone and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ganaxolone belongs to Central Nervous System; Voriconazole belongs to Anti Fungals.
Why it happens
Minor CYP3A4-mediated contribution to ganaxolone clearance, with negligible clinical change from inhibition.
What to do
No dose adjustment is required; monitor routinely for sedation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Other interactions of Ganaxolone
Frequently asked questions
Can I take Ganaxolone with Voriconazole?
MediHelp rates the interaction as minor. Ganaxolone and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ganaxolone is metabolized by CYP3A4, but labeling indicates CYP3A4 inhibitors do not meaningfully change its exposure. No clinically significant interaction is expected.
How serious is the interaction between Ganaxolone and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required; monitor routinely for sedation.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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