Drug interactions
Garlic + Nabumetone
Severity: Minor
Garlic and Nabumetone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have antiplatelet activity and may add to the bleeding tendency of NSAIDs. Clinical evidence is limited and mostly based on case reports and in vitro data.
What this interaction means in plain words
Garlic and Nabumetone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Garlic belongs to Gastrointestinal Tract; Nabumetone belongs to Musculoskeletal.
Why it happens
Garlic constituents such as ajoene inhibit platelet aggregation, additive to NSAID platelet inhibition.
What to do
Ask about supplement use and advise patients to report unusual bruising or bleeding. Consider stopping garlic supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabumetone
- Ketorolac intranasal + Nabumetone Contraindicated
- Ketorolac + Nabumetone Contraindicated
- Aceclofenac + Nabumetone Major
- Acemetacin + Nabumetone Major
- Acetylsalicylic acid + Nabumetone Major
- Alteplase + Nabumetone Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Garlic with Nabumetone?
MediHelp rates the interaction as minor. Garlic and Nabumetone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have antiplatelet activity and may add to the bleeding tendency of NSAIDs. Clinical evidence is limited and mostly based on case reports and in vitro data.
How serious is the interaction between Garlic and Nabumetone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about supplement use and advise patients to report unusual bruising or bleeding. Consider stopping garlic supplements before surgery.
What other medicines interact with Nabumetone?
MediHelp also lists interactions of Nabumetone with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Nabumetone page.
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