Drug interactions
Garlic + Piroxicam
Severity: Minor
Garlic and Piroxicam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have mild antiplatelet activity and may add to the bleeding tendency of NSAIDs. Evidence is limited to case reports and laboratory data.
What this interaction means in plain words
Garlic and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Garlic belongs to Gastrointestinal Tract; Piroxicam belongs to Musculoskeletal.
Why it happens
Garlic constituents inhibit platelet aggregation, additive to NSAID platelet inhibition.
What to do
Advise patients to report unusual bruising or bleeding and consider stopping garlic supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Garlic with Piroxicam?
MediHelp rates the interaction as minor. Garlic and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have mild antiplatelet activity and may add to the bleeding tendency of NSAIDs. Evidence is limited to case reports and laboratory data.
How serious is the interaction between Garlic and Piroxicam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report unusual bruising or bleeding and consider stopping garlic supplements before surgery.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
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