Drug interactions
Gliclazide + Mesterolone
Severity: Minor
Gliclazide and Mesterolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens can improve insulin sensitivity and lower blood glucose, which may enhance the effect of sulfonylureas. Hypoglycemia is possible but infrequent.
What this interaction means in plain words
Gliclazide and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gliclazide belongs to Endocrine; Mesterolone belongs to Endocrine.
Why it happens
Additive glucose-lowering through androgen effects on insulin sensitivity.
What to do
Monitor blood glucose when mesterolone is started or stopped. Reduce the gliclazide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Other interactions of Mesterolone
Frequently asked questions
Can I take Gliclazide with Mesterolone?
MediHelp rates the interaction as minor. Gliclazide and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens can improve insulin sensitivity and lower blood glucose, which may enhance the effect of sulfonylureas. Hypoglycemia is possible but infrequent.
How serious is the interaction between Gliclazide and Mesterolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when mesterolone is started or stopped. Reduce the gliclazide dose if hypoglycemia occurs.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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