Drug interactions
Glipizide + Oxymetholone
Severity: Moderate
Glipizide and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone is an anabolic steroid that can lower blood glucose and enhance insulin sensitivity. Combined with glipizide it may provoke hypoglycemia.
What this interaction means in plain words
Glipizide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic androgens increase insulin sensitivity, adding to the insulin secretion stimulated by sulfonylureas.
What to do
Check blood glucose more often when starting or stopping oxymetholone. Lower the glipizide dose if glucose values fall or hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Glipizide
Frequently asked questions
Can I take Glipizide with Oxymetholone?
MediHelp rates the interaction as moderate. Glipizide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone is an anabolic steroid that can lower blood glucose and enhance insulin sensitivity. Combined with glipizide it may provoke hypoglycemia.
How serious is the interaction between Glipizide and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often when starting or stopping oxymetholone. Lower the glipizide dose if glucose values fall or hypoglycemia occurs.
What other medicines interact with Glipizide?
MediHelp also lists interactions of Glipizide with, for example, Disopyramide, Fluconazole, Insulin degludec-liraglutide. The full list is on the Glipizide page.
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