Drug interactions
Glipizide + Sage
Severity: Minor
Glipizide and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage preparations have shown glucose-lowering activity in small studies. Used with glipizide they may add to the hypoglycemic effect.
What this interaction means in plain words
Glipizide and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic activity of sage constituents; not well characterized.
What to do
Ask patients about herbal supplement use and monitor blood glucose. Reduce glipizide if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glipizide
Frequently asked questions
Can I take Glipizide with Sage?
MediHelp rates the interaction as minor. Glipizide and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage preparations have shown glucose-lowering activity in small studies. Used with glipizide they may add to the hypoglycemic effect.
How serious is the interaction between Glipizide and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal supplement use and monitor blood glucose. Reduce glipizide if hypoglycemia occurs.
What other medicines interact with Glipizide?
MediHelp also lists interactions of Glipizide with, for example, Disopyramide, Fluconazole, Insulin degludec-liraglutide. The full list is on the Glipizide page.
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