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Drug interactions

Glucagon + Umeclidinium bromide / vilanterol inhaled

Severity: Minor

Glucagon and Umeclidinium bromide / vilanterol inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

The inhaled umeclidinium component has low systemic exposure, so any additive slowing of gut motility with glucagon is expected to be small and transient.

What this interaction means in plain words

Glucagon and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive inhibition of gastrointestinal motility, limited by low systemic antimuscarinic exposure from inhalation.

What to do

No routine change is needed; monitor for constipation or abdominal distension if glucagon is used repeatedly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Glucagon with Umeclidinium bromide / vilanterol inhaled?

MediHelp rates the interaction as minor. Glucagon and Umeclidinium bromide / vilanterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The inhaled umeclidinium component has low systemic exposure, so any additive slowing of gut motility with glucagon is expected to be small and transient.

How serious is the interaction between Glucagon and Umeclidinium bromide / vilanterol inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for constipation or abdominal distension if glucagon is used repeatedly.

What other medicines interact with Glucagon?

MediHelp also lists interactions of Glucagon with, for example, Atropine, Benztropine, Dicyclomine. The full list is on the Glucagon page.

Full monographs, dosing and an interaction checker in the MediHelp app

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