Drug interactions
Glycopyrrolate inhaled + Trimipramine
Severity: Minor
Glycopyrrolate inhaled and Trimipramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are antimuscarinic, so combined use may add to dry mouth, urinary retention, constipation and tachycardia. Systemic exposure from inhaled glycopyrrolate is low, which limits the effect.
What this interaction means in plain words
Glycopyrrolate inhaled and Trimipramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for urinary retention and constipation, especially in older men and patients with narrow-angle glaucoma.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Glycopyrrolate inhaled and Trimipramine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Trimipramine
- Disopyramide + Trimipramine Contraindicated
- Dofetilide + Trimipramine Contraindicated
- Ibutilide + Trimipramine Contraindicated
- Isocarboxazid + Trimipramine Contraindicated
- Pentamidine + Trimipramine Contraindicated
- Phenelzine + Trimipramine Contraindicated
Frequently asked questions
Can I take Glycopyrrolate inhaled with Trimipramine?
MediHelp rates the interaction as minor. Glycopyrrolate inhaled and Trimipramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are antimuscarinic, so combined use may add to dry mouth, urinary retention, constipation and tachycardia. Systemic exposure from inhaled glycopyrrolate is low, which limits the effect.
How serious is the interaction between Glycopyrrolate inhaled and Trimipramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention and constipation, especially in older men and patients with narrow-angle glaucoma.
What other medicines interact with Trimipramine?
MediHelp also lists interactions of Trimipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Trimipramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
