Drug interactions
Golimumab + Haemophilus influenzae type b vaccine
Severity: Minor
Golimumab and Haemophilus influenzae type b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Golimumab may reduce the immune response to the inactivated Hib vaccine, so protection may be lower. The vaccine remains safe to give.
What this interaction means in plain words
Golimumab and Haemophilus influenzae type b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF-alpha inhibition blunts humoral response to vaccine antigens.
What to do
Vaccinate before starting golimumab where feasible, and do not withhold the vaccine during therapy. Consider revaccination if protection is critical.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Haemophilus influenzae type b vaccine?
MediHelp rates the interaction as minor. Golimumab and Haemophilus influenzae type b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Golimumab may reduce the immune response to the inactivated Hib vaccine, so protection may be lower. The vaccine remains safe to give.
How serious is the interaction between Golimumab and Haemophilus influenzae type b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before starting golimumab where feasible, and do not withhold the vaccine during therapy. Consider revaccination if protection is critical.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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