Drug interactions
Golimumab + Hepatitis a / b vaccine
Severity: Minor
Golimumab and Hepatitis a / b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combined hepatitis A/B vaccine is inactivated and safe to give. Golimumab may lower antibody responses, particularly to the hepatitis B component.
What this interaction means in plain words
Golimumab and Hepatitis a / b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF inhibition-related immunosuppression may reduce humoral vaccine responses.
What to do
Vaccinate as indicated and check anti-HBs titres after the series; revaccinate or boost if the response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Hepatitis a / b vaccine?
MediHelp rates the interaction as minor. Golimumab and Hepatitis a / b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The combined hepatitis A/B vaccine is inactivated and safe to give. Golimumab may lower antibody responses, particularly to the hepatitis B component.
How serious is the interaction between Golimumab and Hepatitis a / b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as indicated and check anti-HBs titres after the series; revaccinate or boost if the response is inadequate.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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