Drug interactions
Golimumab + Hepatitis b vaccine
Severity: Minor
Golimumab and Hepatitis b vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hepatitis B vaccine is non-live and recommended for patients on TNF inhibitors. Golimumab may reduce seroconversion or antibody titres.
What this interaction means in plain words
Golimumab and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF inhibition-related immunosuppression may reduce the humoral response.
What to do
Vaccinate and check anti-HBs titres 1 to 2 months after the series, revaccinating with additional or higher doses if the response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Hepatitis b vaccine?
MediHelp rates the interaction as minor. Golimumab and Hepatitis b vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hepatitis B vaccine is non-live and recommended for patients on TNF inhibitors. Golimumab may reduce seroconversion or antibody titres.
How serious is the interaction between Golimumab and Hepatitis b vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate and check anti-HBs titres 1 to 2 months after the series, revaccinating with additional or higher doses if the response is inadequate.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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