Drug interactions
Golimumab + Human papillomavirus vaccine nonavalent
Severity: Minor
Golimumab and Human papillomavirus vaccine nonavalent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
TNF inhibitors can blunt antibody responses to some vaccines, so the HPV vaccine may produce a weaker immune response in patients on golimumab. The vaccine is not live and is not unsafe, but protection may be reduced. The clinical significance for HPV is uncertain, and the vaccine is generally still recommended.
What this interaction means in plain words
Golimumab and Human papillomavirus vaccine nonavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunosuppression from TNF blockade may reduce vaccine-induced antibody responses.
What to do
Vaccinate when indicated, ideally before starting golimumab, and do not delay needed therapy. Complete the full vaccine series.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Human papillomavirus vaccine nonavalent?
MediHelp rates the interaction as minor. Golimumab and Human papillomavirus vaccine nonavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. TNF inhibitors can blunt antibody responses to some vaccines, so the HPV vaccine may produce a weaker immune response in patients on golimumab. The vaccine is not live and is not unsafe, but protection may be reduced. The clinical significance for HPV is uncertain, and the vaccine is generally still recommended.
How serious is the interaction between Golimumab and Human papillomavirus vaccine nonavalent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate when indicated, ideally before starting golimumab, and do not delay needed therapy. Complete the full vaccine series.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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