Drug interactions
Golimumab + Influenza virus vaccine quadrivalent adjuvanted
Severity: Moderate
Golimumab and Influenza virus vaccine quadrivalent adjuvanted: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Golimumab, a TNF blocker, may blunt the antibody response to inactivated influenza vaccine. The vaccine is not harmful in this setting, but protection may be lower than expected in treated patients.
What this interaction means in plain words
Golimumab and Influenza virus vaccine quadrivalent adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
TNF inhibition dampens immune activation and antibody production after vaccination.
What to do
Continue to give inactivated influenza vaccine annually to patients on golimumab, ideally before starting therapy when feasible. Do not rely on vaccination alone and use standard infection-prevention measures.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates the interaction as moderate. Golimumab and Influenza virus vaccine quadrivalent adjuvanted can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Golimumab, a TNF blocker, may blunt the antibody response to inactivated influenza vaccine. The vaccine is not harmful in this setting, but protection may be lower than expected in treated patients.
How serious is the interaction between Golimumab and Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue to give inactivated influenza vaccine annually to patients on golimumab, ideally before starting therapy when feasible. Do not rely on vaccination alone and use standard infection-prevention measures.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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