Drug interactions
Golimumab + Influenza virus vaccine quadrivalent recombinant
Severity: Moderate
Golimumab and Influenza virus vaccine quadrivalent recombinant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
TNF inhibition can reduce antibody responses to inactivated or recombinant influenza vaccines, so protection may be lower. The vaccine is non-live and remains recommended.
What this interaction means in plain words
Golimumab and Influenza virus vaccine quadrivalent recombinant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
TNF blockade dampens immune activation and may reduce vaccine-induced antibody production.
What to do
Give the annual influenza vaccine as scheduled without interrupting golimumab. Evaluate influenza-like illness promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Influenza virus vaccine quadrivalent recombinant?
MediHelp rates the interaction as moderate. Golimumab and Influenza virus vaccine quadrivalent recombinant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. TNF inhibition can reduce antibody responses to inactivated or recombinant influenza vaccines, so protection may be lower. The vaccine is non-live and remains recommended.
How serious is the interaction between Golimumab and Influenza virus vaccine quadrivalent recombinant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the annual influenza vaccine as scheduled without interrupting golimumab. Evaluate influenza-like illness promptly.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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