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Drug interactions

Golimumab + Pneumococcal vaccine heptavalent

Severity: Minor

Golimumab and Pneumococcal vaccine heptavalent: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pneumococcal conjugate vaccine is non-live. Golimumab may somewhat reduce the antibody response but does not add infection risk, and vaccination is recommended in these patients.

What this interaction means in plain words

Golimumab and Pneumococcal vaccine heptavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Moderate

Why it happens

TNF-alpha blockade may modestly reduce vaccine-induced antibody responses.

What to do

Vaccinate per guidelines, preferably before starting golimumab, and continue therapy.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Golimumab with Pneumococcal vaccine heptavalent?

MediHelp rates the interaction as minor. Golimumab and Pneumococcal vaccine heptavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pneumococcal conjugate vaccine is non-live. Golimumab may somewhat reduce the antibody response but does not add infection risk, and vaccination is recommended in these patients.

How serious is the interaction between Golimumab and Pneumococcal vaccine heptavalent?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate per guidelines, preferably before starting golimumab, and continue therapy.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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