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Drug interactions

Golimumab + Poliovirus vaccine inactivated

Severity: Minor

Golimumab and Poliovirus vaccine inactivated: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Golimumab may lower the antibody response to inactivated poliovirus vaccine, although the vaccine is safe to give.

What this interaction means in plain words

Golimumab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

TNF-alpha blockade attenuates the immune response to vaccine antigens.

What to do

Complete inactivated vaccinations before starting golimumab when possible. Do not withhold the vaccine if therapy is already underway.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Golimumab with Poliovirus vaccine inactivated?

MediHelp rates the interaction as minor. Golimumab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Golimumab may lower the antibody response to inactivated poliovirus vaccine, although the vaccine is safe to give.

How serious is the interaction between Golimumab and Poliovirus vaccine inactivated?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete inactivated vaccinations before starting golimumab when possible. Do not withhold the vaccine if therapy is already underway.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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