Drug interactions
Golimumab + Rabies vaccine
Severity: Moderate
Golimumab and Rabies vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rabies vaccines are non-live, but golimumab may reduce the antibody response, which is important when the vaccine is used for post-exposure protection.
What this interaction means in plain words
Golimumab and Rabies vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
TNF-alpha blockade may blunt vaccine-induced antibody responses.
What to do
Give the full course, including immune globulin when indicated, and check rabies neutralizing antibody titers after vaccination if the patient is at ongoing risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Rabies vaccine?
MediHelp rates the interaction as moderate. Golimumab and Rabies vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rabies vaccines are non-live, but golimumab may reduce the antibody response, which is important when the vaccine is used for post-exposure protection.
How serious is the interaction between Golimumab and Rabies vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the full course, including immune globulin when indicated, and check rabies neutralizing antibody titers after vaccination if the patient is at ongoing risk.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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