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Drug interactions

Golimumab + Rubella vaccine

Severity: Contraindicated

Golimumab and Rubella vaccine: contraindicated interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Rubella vaccine is live attenuated, and immunosuppression from golimumab may permit vaccine virus replication and illness, while also reducing efficacy.

What this interaction means in plain words

Golimumab and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Evidence level: Moderate

Why it happens

TNF-alpha blockade impairs immune control of replicating live attenuated virus.

What to do

Do not give during golimumab therapy; vaccinate before starting when possible and follow guidelines on intervals after stopping.

What to ask your pharmacist

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Golimumab with Rubella vaccine?

MediHelp rates the interaction as contraindicated. Golimumab and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rubella vaccine is live attenuated, and immunosuppression from golimumab may permit vaccine virus replication and illness, while also reducing efficacy.

How serious is the interaction between Golimumab and Rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give during golimumab therapy; vaccinate before starting when possible and follow guidelines on intervals after stopping.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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