Drug interactions
Golimumab + Zoster vaccine live
Severity: Contraindicated
Golimumab and Zoster vaccine live: contraindicated interaction.
Last updated Sources: US FDA label
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Live zoster vaccine may cause disseminated varicella-zoster vaccine-strain infection in patients on golimumab, and the response may be reduced.
What this interaction means in plain words
Golimumab and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
TNF-alpha blockade impairs immune control of replicating live attenuated virus.
What to do
Do not give the live vaccine during golimumab therapy; use the recombinant non-live zoster vaccine where indicated.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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References
Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Zoster vaccine live?
MediHelp rates the interaction as contraindicated. Golimumab and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live zoster vaccine may cause disseminated varicella-zoster vaccine-strain infection in patients on golimumab, and the response may be reduced.
How serious is the interaction between Golimumab and Zoster vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during golimumab therapy; use the recombinant non-live zoster vaccine where indicated.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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