Drug interactions
Golimumab + Zoster vaccine recombinant
Severity: Minor
Golimumab and Zoster vaccine recombinant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Golimumab may reduce the immune response to the recombinant zoster vaccine. Protection against shingles may be less complete than in non-immunosuppressed patients, though the vaccine is non-live and can be given.
What this interaction means in plain words
Golimumab and Zoster vaccine recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF blockade dampens vaccine-induced humoral and cellular immune responses.
What to do
Vaccinate eligible patients, ideally before starting or at a convenient point in golimumab therapy; do not withhold the vaccine. Complete the two-dose series as recommended.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Zoster vaccine recombinant?
MediHelp rates the interaction as minor. Golimumab and Zoster vaccine recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Golimumab may reduce the immune response to the recombinant zoster vaccine. Protection against shingles may be less complete than in non-immunosuppressed patients, though the vaccine is non-live and can be given.
How serious is the interaction between Golimumab and Zoster vaccine recombinant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate eligible patients, ideally before starting or at a convenient point in golimumab therapy; do not withhold the vaccine. Complete the two-dose series as recommended.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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