Drug interactions
Green tea + Modafinil
Severity: Minor
Green tea and Modafinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Green tea contains caffeine, which has additive stimulant effects with modafinil. Large amounts may cause insomnia, nervousness, tremor and palpitations.
What this interaction means in plain words
Green tea and Modafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Green tea belongs to Gastrointestinal Tract; Modafinil belongs to Central Nervous System.
Why it happens
Additive CNS stimulation from the caffeine content of green tea.
What to do
Advise limiting green tea intake, especially later in the day, and monitor for insomnia and tachycardia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Modafinil
Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Frequently asked questions
Can I take Green tea with Modafinil?
MediHelp rates the interaction as minor. Green tea and Modafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Green tea contains caffeine, which has additive stimulant effects with modafinil. Large amounts may cause insomnia, nervousness, tremor and palpitations.
How serious is the interaction between Green tea and Modafinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise limiting green tea intake, especially later in the day, and monitor for insomnia and tachycardia.
What other medicines interact with Modafinil?
MediHelp also lists interactions of Modafinil with, for example, Lenacapavir, Leniolisib, Lorlatinib. The full list is on the Modafinil page.
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