Drug reference
modafinil
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (CNS Stimulants)
Mechanism of action
Unknown; not sympathomimetic; may increase dopamine levels in the brain by binding to the dopamine transporter and inhibiting dopamine reuptake
Common side effects
- Decreased appetite
- Headache
- Nausea
- Rhinitis
- Abdominal pain
Known interactions (2)
- isocarboxazid + modafinil Moderate
- modafinil + Sertraline Moderate
Related conditions
Frequently asked questions
What drug class is modafinil?
modafinil belongs to: Central Nervous System.
How does modafinil work?
Unknown; not sympathomimetic; may increase dopamine levels in the brain by binding to the dopamine transporter and inhibiting dopamine reuptake
What are the common side effects of modafinil?
Decreased appetite, Headache, Nausea, Rhinitis, Abdominal pain
Which drugs interact with modafinil?
isocarboxazid, Sertraline
Full monographs, dosing and an interaction checker in the MediHelp app
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