Drug interactions
Guarana + Methamphetamine
Severity: Minor
Guarana and Methamphetamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Guarana contains caffeine and related methylxanthines that stimulate the central nervous system. Taken with methamphetamine, it may add to tachycardia, hypertension, anxiety, insomnia and palpitations.
What this interaction means in plain words
Guarana and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive sympathomimetic and CNS stimulant effects of caffeine in guarana with methamphetamine.
What to do
Advise patients to limit guarana and other caffeine-containing products while on methamphetamine. Monitor heart rate and blood pressure if use continues.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Guarana with Methamphetamine?
MediHelp rates the interaction as minor. Guarana and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Guarana contains caffeine and related methylxanthines that stimulate the central nervous system. Taken with methamphetamine, it may add to tachycardia, hypertension, anxiety, insomnia and palpitations.
How serious is the interaction between Guarana and Methamphetamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to limit guarana and other caffeine-containing products while on methamphetamine. Monitor heart rate and blood pressure if use continues.
What other medicines interact with Methamphetamine?
MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.
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