Drug interactions
Hepatitis a / b vaccine + Hydroxychloroquine
Severity: Minor
Hepatitis a / b vaccine and Hydroxychloroquine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This combination vaccine is non-live, and hydroxychloroquine is unlikely to impair the immune response in a clinically significant way. No important interaction is expected.
What this interaction means in plain words
Hepatitis a / b vaccine and Hydroxychloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Slight immunomodulation by hydroxychloroquine may theoretically reduce antibody response; not firmly established.
What to do
Complete the vaccine series as scheduled; check anti-HBs titres only if risk factors warrant it.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hepatitis a / b vaccine and Hydroxychloroquine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hepatitis a / b vaccine with Hydroxychloroquine?
MediHelp rates the interaction as minor. Hepatitis a / b vaccine and Hydroxychloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This combination vaccine is non-live, and hydroxychloroquine is unlikely to impair the immune response in a clinically significant way. No important interaction is expected.
How serious is the interaction between Hepatitis a / b vaccine and Hydroxychloroquine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the vaccine series as scheduled; check anti-HBs titres only if risk factors warrant it.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
