Drug interactions
Human papillomavirus vaccine nonavalent + Infliximab
Severity: Minor
Human papillomavirus vaccine nonavalent and Infliximab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Infliximab may reduce the antibody response to vaccines, so protection from the HPV vaccine may be weaker. The vaccine is non-live and is not unsafe in this setting.
What this interaction means in plain words
Human papillomavirus vaccine nonavalent and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF blockade may blunt the humoral immune response to vaccination.
What to do
Vaccinate according to schedule, ideally before starting infliximab where possible. Do not withhold the vaccine, and complete the full series.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Infliximab
- Bcg vaccine live + Infliximab Contraindicated
- Infliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Infliximab + Measles mumps and rubella vaccine Contraindicated
- Infliximab + Measles mumps and rubella vaccine live Contraindicated
- Infliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Infliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Human papillomavirus vaccine nonavalent with Infliximab?
MediHelp rates the interaction as minor. Human papillomavirus vaccine nonavalent and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Infliximab may reduce the antibody response to vaccines, so protection from the HPV vaccine may be weaker. The vaccine is non-live and is not unsafe in this setting.
How serious is the interaction between Human papillomavirus vaccine nonavalent and Infliximab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate according to schedule, ideally before starting infliximab where possible. Do not withhold the vaccine, and complete the full series.
What other medicines interact with Infliximab?
MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.
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