Drug interactions
Hydrochlorothiazide + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can promote potassium loss, and systemic exposure to inhaled mometasone is low. At usual inhaled doses the added hypokalemic effect with hydrochlorothiazide is likely small.
What this interaction means in plain words
Hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid-like potassium wasting from corticosteroids may add to thiazide kaliuresis, but is minimal with inhaled use.
What to do
No routine action; check potassium if high-dose inhaled steroid is used or other hypokalemia risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide
Frequently asked questions
Can I take Hydrochlorothiazide with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can promote potassium loss, and systemic exposure to inhaled mometasone is low. At usual inhaled doses the added hypokalemic effect with hydrochlorothiazide is likely small.
How serious is the interaction between Hydrochlorothiazide and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; check potassium if high-dose inhaled steroid is used or other hypokalemia risk factors are present.
What other medicines interact with Hydrochlorothiazide?
MediHelp also lists interactions of Hydrochlorothiazide with, for example, Dofetilide, Amifostine, Amiodarone. The full list is on the Hydrochlorothiazide page.
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