Drug interactions
Hydrochlorothiazide-irbesartan + Mometasone inhaled
Severity: Minor
Hydrochlorothiazide-irbesartan and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can cause potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone, systemic exposure is low, so the effect is usually small.
What this interaction means in plain words
Hydrochlorothiazide-irbesartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid activity of corticosteroids increases renal potassium excretion, adding to thiazide kaliuresis.
What to do
Periodically check serum potassium, especially with high inhaled doses or other potassium-lowering drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-irbesartan
- Aliskiren + Hydrochlorothiazide-irbesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-irbesartan Contraindicated
- Hydrochlorothiazide-irbesartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-irbesartan Major
- Amifostine + Hydrochlorothiazide-irbesartan Major
- Amiloride + Hydrochlorothiazide-irbesartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-irbesartan with Mometasone inhaled?
MediHelp rates the interaction as minor. Hydrochlorothiazide-irbesartan and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can cause potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone, systemic exposure is low, so the effect is usually small.
How serious is the interaction between Hydrochlorothiazide-irbesartan and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Periodically check serum potassium, especially with high inhaled doses or other potassium-lowering drugs.
What other medicines interact with Hydrochlorothiazide-irbesartan?
MediHelp also lists interactions of Hydrochlorothiazide-irbesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-irbesartan page.
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