Drug interactions
Hydrochlorothiazide-irbesartan + Pindolol
Severity: Minor
Hydrochlorothiazide-irbesartan and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol combined with irbesartan and hydrochlorothiazide gives additive blood pressure reduction, which may lead to hypotension or bradycardia. Beta-blockers can slightly increase potassium, adding to the effect of the ARB.
What this interaction means in plain words
Hydrochlorothiazide-irbesartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects and a small beta-blocker-related shift of potassium out of cells.
What to do
Monitor blood pressure, heart rate and serum potassium when initiating or adjusting therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-irbesartan
- Aliskiren + Hydrochlorothiazide-irbesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-irbesartan Contraindicated
- Hydrochlorothiazide-irbesartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-irbesartan Major
- Amifostine + Hydrochlorothiazide-irbesartan Major
- Amiloride + Hydrochlorothiazide-irbesartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-irbesartan with Pindolol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-irbesartan and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pindolol combined with irbesartan and hydrochlorothiazide gives additive blood pressure reduction, which may lead to hypotension or bradycardia. Beta-blockers can slightly increase potassium, adding to the effect of the ARB.
How serious is the interaction between Hydrochlorothiazide-irbesartan and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium when initiating or adjusting therapy.
What other medicines interact with Hydrochlorothiazide-irbesartan?
MediHelp also lists interactions of Hydrochlorothiazide-irbesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-irbesartan page.
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