Drug interactions
Hydrochlorothiazide-irbesartan + Triamcinolone acetonide injectable
Severity: Moderate
Hydrochlorothiazide-irbesartan and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroid exposure from triamcinolone injection may promote potassium loss, adding to the effect of hydrochlorothiazide. Hypokalemia is more likely with repeated or high doses.
What this interaction means in plain words
Hydrochlorothiazide-irbesartan and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive renal potassium wasting.
What to do
Monitor serum potassium when repeated or high systemic doses are given, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-irbesartan
- Aliskiren + Hydrochlorothiazide-irbesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-irbesartan Contraindicated
- Hydrochlorothiazide-irbesartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-irbesartan Major
- Amifostine + Hydrochlorothiazide-irbesartan Major
- Amiloride + Hydrochlorothiazide-irbesartan Major
Frequently asked questions
Can I take Hydrochlorothiazide-irbesartan with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-irbesartan and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroid exposure from triamcinolone injection may promote potassium loss, adding to the effect of hydrochlorothiazide. Hypokalemia is more likely with repeated or high doses.
How serious is the interaction between Hydrochlorothiazide-irbesartan and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium when repeated or high systemic doses are given, and replace potassium as needed.
What other medicines interact with Hydrochlorothiazide-irbesartan?
MediHelp also lists interactions of Hydrochlorothiazide-irbesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-irbesartan page.
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