Drug interactions
Hydrochlorothiazide-olmesartan + Miglitol
Severity: Minor
Hydrochlorothiazide-olmesartan and Miglitol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics can raise blood glucose and may partly offset the glucose-lowering effect of miglitol. The effect is generally small at usual hydrochlorothiazide doses.
What this interaction means in plain words
Hydrochlorothiazide-olmesartan and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-olmesartan belongs to Cardiovascular; Miglitol belongs to Endocrine.
Why it happens
Thiazides reduce insulin secretion and sensitivity, opposing the antidiabetic action.
What to do
Monitor blood glucose after starting or changing the thiazide and adjust diabetes therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Frequently asked questions
Can I take Hydrochlorothiazide-olmesartan with Miglitol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-olmesartan and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics can raise blood glucose and may partly offset the glucose-lowering effect of miglitol. The effect is generally small at usual hydrochlorothiazide doses.
How serious is the interaction between Hydrochlorothiazide-olmesartan and Miglitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or changing the thiazide and adjust diabetes therapy if needed.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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