Drug interactions
Hydrochlorothiazide-telmisartan + Magnesium hydroxide
Severity: Minor
Hydrochlorothiazide-telmisartan and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics promote urinary magnesium loss, so long-term use may lower serum magnesium. Oral magnesium hydroxide is mostly unabsorbed, so any offsetting effect is small and of little clinical importance.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Magnesium hydroxide belongs to Gastrointestinal Tract.
Why it happens
Hydrochlorothiazide increases renal magnesium excretion, which may slightly reduce systemic magnesium exposure.
What to do
No routine action is needed. Check serum magnesium in patients on long-term thiazide therapy who have symptoms or other risk factors for hypomagnesemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Magnesium hydroxide
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Magnesium hydroxide?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics promote urinary magnesium loss, so long-term use may lower serum magnesium. Oral magnesium hydroxide is mostly unabsorbed, so any offsetting effect is small and of little clinical importance.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Check serum magnesium in patients on long-term thiazide therapy who have symptoms or other risk factors for hypomagnesemia.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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