Drug interactions
Hydrochlorothiazide-telmisartan + Magnesium oxide
Severity: Minor
Hydrochlorothiazide-telmisartan and Magnesium oxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides increase urinary magnesium loss and can cause hypomagnesemia, which may partly offset magnesium supplementation. The effect is usually modest.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Magnesium oxide belongs to Gastrointestinal Tract.
Why it happens
Thiazide-induced increase in renal magnesium excretion.
What to do
Monitor serum magnesium in long-term thiazide therapy and adjust the supplement dose accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Magnesium oxide
- Chloroquine + Magnesium oxide Moderate
- Ciprofloxacin + Magnesium oxide Moderate
- Dolutegravir + Magnesium oxide Moderate
- Doxycycline + Magnesium oxide Moderate
- Eltrombopag + Magnesium oxide Moderate
- Gemifloxacin + Magnesium oxide Moderate
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Magnesium oxide?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides increase urinary magnesium loss and can cause hypomagnesemia, which may partly offset magnesium supplementation. The effect is usually modest.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Magnesium oxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium in long-term thiazide therapy and adjust the supplement dose accordingly.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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