Drug interactions
Hydrochlorothiazide-telmisartan + Metoprolol
Severity: Minor
Hydrochlorothiazide-telmisartan and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-blockers and ARB/thiazide combinations are commonly used together and produce additive blood pressure lowering. Excess hypotension, bradycardia or dizziness may occur, and thiazides may modestly worsen glucose and lipid parameters in patients on beta-blockers.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Metoprolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamic effects from different mechanisms.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses. Reduce doses if symptomatic hypotension or bradycardia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Metoprolol?
MediHelp rates the interaction as minor. Hydrochlorothiazide-telmisartan and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Beta-blockers and ARB/thiazide combinations are commonly used together and produce additive blood pressure lowering. Excess hypotension, bradycardia or dizziness may occur, and thiazides may modestly worsen glucose and lipid parameters in patients on beta-blockers.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses. Reduce doses if symptomatic hypotension or bradycardia develops.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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