Drug interactions
Hydrochlorothiazide-telmisartan + Potassium iodide
Severity: Moderate
Hydrochlorothiazide-telmisartan and Potassium iodide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies a potassium load, and telmisartan limits potassium elimination, so hyperkalemia is possible, especially with renal impairment or prolonged use. At typical short-course or low doses the potassium amount is small, so the risk is mostly in susceptible patients. Hydrochlorothiazide partly counteracts this.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Potassium iodide belongs to Endocrine.
Why it happens
Additive potassium load with reduced renal potassium excretion from angiotensin receptor blockade.
What to do
Monitor serum potassium if potassium iodide is given repeatedly or at high doses, particularly in patients with reduced renal function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Potassium iodide?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide supplies a potassium load, and telmisartan limits potassium elimination, so hyperkalemia is possible, especially with renal impairment or prolonged use. At typical short-course or low doses the potassium amount is small, so the risk is mostly in susceptible patients. Hydrochlorothiazide partly counteracts this.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Potassium iodide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if potassium iodide is given repeatedly or at high doses, particularly in patients with reduced renal function.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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