Drug interactions
Hydrocortisone + Indacaterol
Severity: Minor
Hydrocortisone and Indacaterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids and long-acting beta-2 agonists may each lower serum potassium, so the combination can cause additive hypokalemia. This matters most in patients with severe COPD or asthma, hypoxia, or cardiac disease.
What this interaction means in plain words
Hydrocortisone and Indacaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydrocortisone belongs to Endocrine; Indacaterol belongs to Respiratory.
Why it happens
Beta-2 agonists drive potassium into cells, while corticosteroids with mineralocorticoid activity increase renal potassium excretion.
What to do
Check serum potassium in patients receiving systemic hydrocortisone, especially at higher doses or with other potassium-lowering drugs. Supplement potassium if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indacaterol
Other interactions of Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicated
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contraindicated
- Hydrocortisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Hydrocortisone Major
- Aldesleukin + Hydrocortisone Major
- Aspirin + Hydrocortisone Major
Frequently asked questions
Can I take Hydrocortisone with Indacaterol?
MediHelp rates the interaction as minor. Hydrocortisone and Indacaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids and long-acting beta-2 agonists may each lower serum potassium, so the combination can cause additive hypokalemia. This matters most in patients with severe COPD or asthma, hypoxia, or cardiac disease.
How serious is the interaction between Hydrocortisone and Indacaterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium in patients receiving systemic hydrocortisone, especially at higher doses or with other potassium-lowering drugs. Supplement potassium if needed.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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