Drug interactions
Hydroxychloroquine + Indacaterol inhaled
Severity: Minor
Hydroxychloroquine and Indacaterol inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled indacaterol, a long-acting beta2-agonist, can cause small QT prolongation and hypokalemia at high exposure. With hydroxychloroquine, there may be a modest additional effect on QT, although inhaled doses give limited systemic exposure.
What this interaction means in plain words
Hydroxychloroquine and Indacaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Beta2-agonist-related hypokalemia and modest QT effects may add to hydroxychloroquine-related QT prolongation.
What to do
No routine change is needed in most patients. Check the ECG and potassium in those with other QT risk factors or heart disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Indacaterol inhaled?
MediHelp rates the interaction as minor. Hydroxychloroquine and Indacaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled indacaterol, a long-acting beta2-agonist, can cause small QT prolongation and hypokalemia at high exposure. With hydroxychloroquine, there may be a modest additional effect on QT, although inhaled doses give limited systemic exposure.
How serious is the interaction between Hydroxychloroquine and Indacaterol inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed in most patients. Check the ECG and potassium in those with other QT risk factors or heart disease.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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