Drug interactions
Hydroxychloroquine + Influenza virus vaccine quadrivalent cell-cultured
Severity: Minor
Hydroxychloroquine and Influenza virus vaccine quadrivalent cell-cultured: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This inactivated influenza vaccine is safe in patients taking hydroxychloroquine, and any reduction in response is expected to be small. Annual vaccination is recommended in patients with rheumatic disease.
What this interaction means in plain words
Hydroxychloroquine and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mild immunomodulation may theoretically dampen antibody response; not well established.
What to do
Give the vaccine annually; no change to hydroxychloroquine is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates the interaction as minor. Hydroxychloroquine and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This inactivated influenza vaccine is safe in patients taking hydroxychloroquine, and any reduction in response is expected to be small. Annual vaccination is recommended in patients with rheumatic disease.
How serious is the interaction between Hydroxychloroquine and Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine annually; no change to hydroxychloroquine is needed.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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