Drug interactions
Hydroxychloroquine + Rabies vaccine chick embryo cell derived
Severity: Moderate
Hydroxychloroquine and Rabies vaccine chick embryo cell derived: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine, a closely related drug, has been reported to reduce the antibody response to intradermal rabies vaccine. Hydroxychloroquine is expected to behave similarly to a lesser degree, particularly with pre-exposure intradermal regimens. The vaccine is non-live, so there is no infection risk from the vaccine itself.
What this interaction means in plain words
Hydroxychloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible blunting of the antibody response through immunomodulatory effects, extrapolated from chloroquine data.
What to do
Use the intramuscular route and consider measuring neutralizing antibody titres after pre-exposure vaccination.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hydroxychloroquine and Rabies vaccine chick embryo cell derived, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Rabies vaccine chick embryo cell derived?
MediHelp rates the interaction as moderate. Hydroxychloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine, a closely related drug, has been reported to reduce the antibody response to intradermal rabies vaccine. Hydroxychloroquine is expected to behave similarly to a lesser degree, particularly with pre-exposure intradermal regimens. The vaccine is non-live, so there is no infection risk from the vaccine itself.
How serious is the interaction between Hydroxychloroquine and Rabies vaccine chick embryo cell derived?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the intramuscular route and consider measuring neutralizing antibody titres after pre-exposure vaccination.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
