Drug interactions
Hydroxychloroquine + Vilanterol / fluticasone furoate inhaled
Severity: Minor
Hydroxychloroquine and Vilanterol / fluticasone furoate inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled vilanterol is a beta-agonist with minimal systemic exposure at labeled doses, so clinically meaningful QT prolongation with hydroxychloroquine is unlikely. Any additive effect would be small and mainly relevant in patients with other risk factors.
What this interaction means in plain words
Hydroxychloroquine and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive QT effect from beta-agonist-related repolarization changes and hypokalemia.
What to do
No routine action needed; check ECG and potassium in patients with existing QT risk factors or high doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as minor. Hydroxychloroquine and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled vilanterol is a beta-agonist with minimal systemic exposure at labeled doses, so clinically meaningful QT prolongation with hydroxychloroquine is unlikely. Any additive effect would be small and mainly relevant in patients with other risk factors.
How serious is the interaction between Hydroxychloroquine and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action needed; check ECG and potassium in patients with existing QT risk factors or high doses.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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