Drug interactions
Hydroxyzine + Telavancin
Severity: Moderate
Hydroxyzine and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxyzine is a known QT-prolonging agent and telavancin may also lengthen the QTc. Combined use may increase the likelihood of torsades de pointes, especially in older patients or those with cardiac disease.
What this interaction means in plain words
Hydroxyzine and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydroxyzine belongs to Respiratory; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QTc prolongation, with hydroxyzine blocking hERG potassium channels.
What to do
Use the lowest effective hydroxyzine dose or an alternative antihistamine or anxiolytic when possible. Monitor ECG and keep potassium and magnesium within normal range.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Frequently asked questions
Can I take Hydroxyzine with Telavancin?
MediHelp rates the interaction as moderate. Hydroxyzine and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydroxyzine is a known QT-prolonging agent and telavancin may also lengthen the QTc. Combined use may increase the likelihood of torsades de pointes, especially in older patients or those with cardiac disease.
How serious is the interaction between Hydroxyzine and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective hydroxyzine dose or an alternative antihistamine or anxiolytic when possible. Monitor ECG and keep potassium and magnesium within normal range.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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