Drug interactions
Ifosfamide + Ixekizumab
Severity: Moderate
Ifosfamide and Ixekizumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ifosfamide is myelosuppressive and immunosuppressive, and ixekizumab (IL-17A inhibitor) can increase susceptibility to infections. Combined use may raise infection risk.
What this interaction means in plain words
Ifosfamide and Ixekizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ifosfamide belongs to Oncology; Ixekizumab belongs to Miscellaneous.
Why it happens
Additive immunosuppression.
What to do
Monitor for infection and consider holding ixekizumab during myelosuppressive chemotherapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicated
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicated
- Ifosfamide + Measles vaccine Contraindicated
- Ifosfamide + Rotavirus oral vaccine live Contraindicated
Other interactions of Ixekizumab
Frequently asked questions
Can I take Ifosfamide with Ixekizumab?
MediHelp rates the interaction as moderate. Ifosfamide and Ixekizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ifosfamide is myelosuppressive and immunosuppressive, and ixekizumab (IL-17A inhibitor) can increase susceptibility to infections. Combined use may raise infection risk.
How serious is the interaction between Ifosfamide and Ixekizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infection and consider holding ixekizumab during myelosuppressive chemotherapy.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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