Drug interactions
Iloperidone + Telavancin
Severity: Major
Iloperidone and Telavancin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone prolongs the QTc interval and telavancin may add to this effect. The combination raises the risk of torsades de pointes, particularly with bradycardia or electrolyte disturbance.
What this interaction means in plain words
Iloperidone and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Iloperidone belongs to Central Nervous System; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation.
What to do
Avoid if possible by choosing another antibiotic. If necessary, monitor ECG and correct potassium and magnesium.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Iloperidone with Telavancin?
MediHelp rates the interaction as major. Iloperidone and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Iloperidone prolongs the QTc interval and telavancin may add to this effect. The combination raises the risk of torsades de pointes, particularly with bradycardia or electrolyte disturbance.
How serious is the interaction between Iloperidone and Telavancin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible by choosing another antibiotic. If necessary, monitor ECG and correct potassium and magnesium.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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