Drug interactions
Iloprost + Isoflurane
Severity: Moderate
Iloprost and Isoflurane: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both isoflurane and iloprost cause vasodilation, so combining them can produce additive hypotension. This is most relevant with intravenous iloprost during anesthesia.
What this interaction means in plain words
Iloprost and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloprost belongs to Cardiovascular; Isoflurane belongs to Central Nervous System.
Why it happens
Additive vasodilatory and hypotensive effects.
What to do
Monitor blood pressure continuously and treat hypotension with fluids or vasopressors. Reduce the iloprost dose if hypotension persists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isoflurane
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Iloprost with Isoflurane?
MediHelp rates the interaction as moderate. Iloprost and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both isoflurane and iloprost cause vasodilation, so combining them can produce additive hypotension. This is most relevant with intravenous iloprost during anesthesia.
How serious is the interaction between Iloprost and Isoflurane?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure continuously and treat hypotension with fluids or vasopressors. Reduce the iloprost dose if hypotension persists.
What other medicines interact with Isoflurane?
MediHelp also lists interactions of Isoflurane with, for example, Adrenaline-articaine, Amisulpride, Arsenic trioxide. The full list is on the Isoflurane page.
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