Drug interactions
Imaging agents + Sotalol
Severity: Moderate
Imaging agents and Sotalol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Patients taking beta-blockers may have more severe or treatment-resistant reactions to iodinated contrast media, since beta-blockade can blunt the response to epinephrine. The legacy mention of gadolinium is nonspecific.
What this interaction means in plain words
Imaging agents and Sotalol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Beta-blockade antagonizes the beta-adrenergic response to epinephrine used to treat anaphylaxis.
What to do
Ensure resuscitation equipment is available and glucagon is on hand for epinephrine-resistant reactions. Do not stop sotalol routinely.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Imaging agents and Sotalol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Frequently asked questions
Can I take Imaging agents with Sotalol?
MediHelp rates the interaction as moderate. Imaging agents and Sotalol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients taking beta-blockers may have more severe or treatment-resistant reactions to iodinated contrast media, since beta-blockade can blunt the response to epinephrine. The legacy mention of gadolinium is nonspecific.
How serious is the interaction between Imaging agents and Sotalol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure resuscitation equipment is available and glucagon is on hand for epinephrine-resistant reactions. Do not stop sotalol routinely.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
