Drug interactions
Imidapril + Meloxicam
Severity: Moderate
Imidapril and Meloxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs can reduce the blood pressure lowering effect of ACE inhibitors and, together, may impair renal function, especially in elderly or volume-depleted patients.
What this interaction means in plain words
Imidapril and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Imidapril belongs to Cardiovascular; Meloxicam belongs to Musculoskeletal.
Why it happens
NSAID inhibition of vasodilatory prostaglandins opposes ACE inhibitor effect and reduces glomerular perfusion.
What to do
Monitor blood pressure, serum creatinine and potassium, and ensure adequate hydration. Use the lowest effective meloxicam dose for the shortest duration.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Other interactions of Imidapril
- Amiloride + Imidapril Major
- Eplerenone + Imidapril Major
- Imidapril + Lithium Major
- Imidapril + Pregabalin Major
- Imidapril + Spironolactone Major
- Imidapril + Triamterene Major
Frequently asked questions
Can I take Imidapril with Meloxicam?
MediHelp rates the interaction as moderate. Imidapril and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs can reduce the blood pressure lowering effect of ACE inhibitors and, together, may impair renal function, especially in elderly or volume-depleted patients.
How serious is the interaction between Imidapril and Meloxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum creatinine and potassium, and ensure adequate hydration. Use the lowest effective meloxicam dose for the shortest duration.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
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