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Drug interactions

Imidapril + Terazosin

Severity: Moderate

Imidapril and Terazosin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Together these drugs can cause additive blood pressure reduction, with an exaggerated first-dose response leading to dizziness or fainting.

What this interaction means in plain words

Imidapril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Imidapril belongs to Cardiovascular; Terazosin belongs to Genitourinary.

Evidence level: Moderate

Why it happens

Additive pharmacodynamic effect of alpha-1 blockade and ACE inhibition.

What to do

Use low starting doses, give the first dose at bedtime, and monitor orthostatic blood pressure during titration.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Imidapril with Terazosin?

MediHelp rates the interaction as moderate. Imidapril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Together these drugs can cause additive blood pressure reduction, with an exaggerated first-dose response leading to dizziness or fainting.

How serious is the interaction between Imidapril and Terazosin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use low starting doses, give the first dose at bedtime, and monitor orthostatic blood pressure during titration.

What other medicines interact with Terazosin?

MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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