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Drug interactions

Indacaterol + Romidepsin

Severity: Moderate

Indacaterol and Romidepsin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Romidepsin can prolong the QT interval, and long-acting beta-agonists such as indacaterol can have cardiac and electrolyte effects. Together they may raise the risk of ventricular arrhythmias.

What this interaction means in plain words

Indacaterol and Romidepsin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive QT prolongation and beta-agonist related hypokalemia.

What to do

Check baseline ECG and correct potassium and magnesium before and during therapy. Monitor for palpitations or syncope.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Indacaterol with Romidepsin?

MediHelp rates the interaction as moderate. Indacaterol and Romidepsin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Romidepsin can prolong the QT interval, and long-acting beta-agonists such as indacaterol can have cardiac and electrolyte effects. Together they may raise the risk of ventricular arrhythmias.

How serious is the interaction between Indacaterol and Romidepsin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and correct potassium and magnesium before and during therapy. Monitor for palpitations or syncope.

What other medicines interact with Indacaterol?

MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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