Drug interactions
Indacaterol + Romidepsin
Severity: Moderate
Indacaterol and Romidepsin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Romidepsin can prolong the QT interval, and long-acting beta-agonists such as indacaterol can have cardiac and electrolyte effects. Together they may raise the risk of ventricular arrhythmias.
What this interaction means in plain words
Indacaterol and Romidepsin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta-agonist related hypokalemia.
What to do
Check baseline ECG and correct potassium and magnesium before and during therapy. Monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Frequently asked questions
Can I take Indacaterol with Romidepsin?
MediHelp rates the interaction as moderate. Indacaterol and Romidepsin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Romidepsin can prolong the QT interval, and long-acting beta-agonists such as indacaterol can have cardiac and electrolyte effects. Together they may raise the risk of ventricular arrhythmias.
How serious is the interaction between Indacaterol and Romidepsin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and correct potassium and magnesium before and during therapy. Monitor for palpitations or syncope.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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