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Drug interactions

Indacaterol + Thiothixene

Severity: Moderate

Indacaterol and Thiothixene: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Thiothixene, an antipsychotic, may prolong the QT interval, and indacaterol may contribute through cardiac stimulation and hypokalemia. The combination may increase arrhythmia risk.

What this interaction means in plain words

Indacaterol and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive QT prolongation and beta-agonist related hypokalemia.

What to do

Monitor ECG and electrolytes, particularly in patients with heart disease or other QT risk factors.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Indacaterol with Thiothixene?

MediHelp rates the interaction as moderate. Indacaterol and Thiothixene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiothixene, an antipsychotic, may prolong the QT interval, and indacaterol may contribute through cardiac stimulation and hypokalemia. The combination may increase arrhythmia risk.

How serious is the interaction between Indacaterol and Thiothixene?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, particularly in patients with heart disease or other QT risk factors.

What other medicines interact with Indacaterol?

MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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