Drug interactions
Indacaterol + Trifluoperazine
Severity: Moderate
Indacaterol and Trifluoperazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trifluoperazine, a phenothiazine, can prolong the QT interval, and indacaterol may contribute to arrhythmic risk through adrenergic stimulation and hypokalemia.
What this interaction means in plain words
Indacaterol and Trifluoperazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta-agonist induced hypokalemia.
What to do
Monitor ECG and potassium, and avoid further QT-prolonging drugs where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Frequently asked questions
Can I take Indacaterol with Trifluoperazine?
MediHelp rates the interaction as moderate. Indacaterol and Trifluoperazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trifluoperazine, a phenothiazine, can prolong the QT interval, and indacaterol may contribute to arrhythmic risk through adrenergic stimulation and hypokalemia.
How serious is the interaction between Indacaterol and Trifluoperazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium, and avoid further QT-prolonging drugs where possible.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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