Drug interactions
Indacaterol-glycopyrronium + Quinine
Severity: Moderate
Indacaterol-glycopyrronium and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine can prolong the QT interval and cause arrhythmias, and indacaterol may add to this effect. Hypokalemia from the beta-agonist can further raise the risk.
What this interaction means in plain words
Indacaterol-glycopyrronium and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Quinine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation.
What to do
Check ECG and electrolytes at baseline in patients with cardiac risk factors. Correct potassium and magnesium and monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Indacaterol-glycopyrronium and Quinine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indacaterol-glycopyrronium
Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Quinine?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine can prolong the QT interval and cause arrhythmias, and indacaterol may add to this effect. Hypokalemia from the beta-agonist can further raise the risk.
How serious is the interaction between Indacaterol-glycopyrronium and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes at baseline in patients with cardiac risk factors. Correct potassium and magnesium and monitor for palpitations or syncope.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
